Recent Advances in Genetic Technique of Microbial Report Cells and Their Applications in Cell Arrays

Table 1

Recent applications of microbial cell arrays.

Application field	Target	Microorganism	Detectable output	References
Environmental monitoring	Mercury	Recombinant Escherichia coli	Fluorescence	[60]
Environmental monitoring	Cadmium and arsenic III	Recombinant E. coli	Bioluminescence	[61]
Environmental monitoring	Silver and titanium oxide nanoparticles	Recombinant E. coli	Gene expression profile	[62]
Environmental monitoring	Endocrine disruptors	Recombinant yeast and E. coli	Bioluminescence	[53]
Environmental monitoring	Cell-damaging stress	Recombinant E. coli	Bioluminescence	[63]
Environmental monitoring	Naphthenic acid	Recombinant E. coli	Fluorescence	[64]
Environmental monitoring	Paraquat, mitomycin C, and salicylic acid	Recombinant E. coli	Bioluminescence	[25]
Disease diagnostics	16 amino acids	Recombinant E. coli auxotroph	Bioluminescence	[33]
Disease diagnostics	Homocysteine	Recombinant E. coli auxotroph	Bioluminescence	[65]
Disease diagnostics	Galactose	Recombinant E. coli auxotroph	Bioluminescence	[66]
Disease diagnostics	Phenylalanine, methionine, and leucine	Recombinant E. coli auxotroph	Fluorescence	[36]
Carbohydrates detection	Mono- and disaccharides	Recombinant E. coli	reduction	[55]
Gene expression analysis	Growth of E. coli colonies	Recombinant E. coli	Gene expression profile	[67]
Screening antibiotics	Antibiotic activity	Staphylococcus aureus	Bioluminescence	[68]
Screening pharmaceuticals	420 pharmaceuticals	Recombinant E. coli	Bioluminescence	[69]