Biomarker Identification and Pathway Analysis by Serum Metabolomics of Lung Cancer

Table 8

ROC curves of potential serum biomarker levels for differentiating the POLC group from the PRLC group.

Marker	Cutoff value	Sensitivity (%)	Specificity (%)	AUC	p value^*	95% CI^a
Sphingosine	86.48	96.67	90.00	0.966	<0.001	0.911
Serine	130.97	80.00	76.67	0.825	<0.001	0.721

 ^*Asymptotic significance, null hypothesis: true area = 0.5.
^a95% confidence interval of the difference.