Research Article

Different Persistence of the Cellular Effects Promoted by Protein Kinase CK2 Inhibitors CX-4945 and TDB

Figure 5

Effects of CX-4945 and TDB on cell migration. Cell migration was assessed by wound-healing assay, seeding U2OS cells in wells containing an insert, and incubating them for 24 h in the presence of the indicated inhibitor (10 μM) or vehicle. Then the insert was removed () and cells were left to migrate for 48 h, always in the presence of the inhibitors (upper part of the figure, “inhibitors maintained”) or in their absence (lower part of the figure, “inhibitors removed”). The experiment was performed three times, with each condition in duplicate. Representative images at ,  h, and  h are shown.
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