Association between Hyperhomocysteinemia and Thyroid Hormones in Euthyroid Diabetic Subjects
Table 2
Correlation of thyroid parameters with hyperhomocysteinaemia.
Hyperhomocysteinaemia
Normal-homocysteine
100
173
Homocysteine (μmol/L)
21.59 ± 11.02
10.76 ± 2.38
0.000
Age (years)
57.87 ± 12.81
52.55 ± 11.14
0.001
0.002
Sex (males/females)
78/22
89/84
0.000
0.000
Duration of diabetes (years)
9.60 ± 7.86
7.63 ± 6.89
0.039
0.678
BMI (kg/m2)
24.92 ± 3.20
25.41 ± 3.94
0.286
0.221
SBP (mmHg)
134.25 ± 17.29
134.61 ± 15.40
0.858
0.777
DBP (mmHg)
81.08 ± 10.91
83.98 ± 9.05
0.019
0.015
TC (mmol/L)
4.80 ± 1.15
4.79 ± 1.02
0.931
0.907
TG (mmol/L)
2.19 ± 2.40
1.88 ± 1.27
0.224
0.035
FBG (mmol/L)
8.39 ± 3.28
9.00 ± 4.08
0.196
0.115
FT3 (pmol/L)
4.49 ± 0.59
4.47 ± 0.49
0.785
0.736
FT4 (pmol/L)
16.15 ± 2.42
16.64 ± 2.24
0.098
0.021
TSH (uIU/mL)
2.23 ± 1.02
2.10 ± 0.93
0.260
0.061
: differences between the two groups by Student’s -tests. : association with hyperhomocysteinaemia by logistic regression analyses and with homocysteine level (1 = hyperhomocysteinaemia, 0 = normal-homocysteine) as dependent variables and independent variables as follows: age, sex, BMI, duration of diabetes, BMI, SBP, DBP, TC, TG, FBG, FT3, FT4, and TSH.
