Research Article

MicroRNA181a Is Overexpressed in T-Cell Leukemia/Lymphoma and Related to Chemoresistance

Table 2

Cross-resistance of doxorubicin-resistant cells to other chemotherapeutic agents.

AgentsIC50 valueIC50 value
JurkatDoxorubicin-resistant JurkatH9Doxorubicin-resistant H9

Cisplatin (uM)6.2 ± 0.3 9.0 ± 0.4 0.00395.7 ± 0.38.5 ± 0.50.0067
Cyclophosphamide (mM)3.3 ± 0.2 4.8 ± 0.2 0.00562.4 ± 0.23.9 ± 0.30.0106