Review Article

A Comprehensive Review on Cyclodextrin-Based Carriers for Delivery of Chemotherapeutic Cytotoxic Anticancer Drugs

Table 3

Cyclodextrin-based carriers of anticancer drugs.

Serial numberDrugCyclodextrinNanocarrier preparedOutcomeReference

1Doxorubicin γ-CDLiposomesIncreased retention in tumor cells[59]
2CurcuminHP-γ-CDLiposomesImprovement in therapeutic efficacy [60]
3Methotrexateβ-CDNiosomesIncreased entrapment efficiency and solubility[61]
4Camptothecinβ-CDNanospongesImprovement in therapeutic efficacy and reduction in toxic effects[62]
5Paclitaxel β-CDNanospongesProlonged shelf life [63]
6Doxorubicin β-cyclodextrin-based star copolymersMicellesEnhanced drug release[64]
7β-lapachoneα-CDPolymeric millirodsSustained drug release[65]
8CamptothecinAmphiphilic β-CDNanoparticlesProlonged drug release[66]
9Paclitaxel Amphiphilic β-CDNanoparticles Increased drug loading capacity[67]
10Docetaxel Amphiphilic β-CDNanoparticlesIncreased solubility and prolonged release[68]