Research Article

Epigenomics of Neural Cells: REST-Induced Down- and Upregulation of Gene Expression in a Two-Clone PC12 Cell Model

Table 1

ENCODE transcription factor (TF) and ChEA database ChIP-seq enrichment analysis using genes downregulated in hrPC12 cells.

DatabaseTerm value-scoreCombined_scoreAdj. value

ChEAREST-18959480-MESC-mouse
ENCODE_TF_ChIP-seq_2015EZH2_B cell_hg19
ChEASUZ12-18692474-MESC-mouse
ChEARNF2-18974828-MESC-MOUSE
ChEAEZH2-18974828-MESC-MOUSE
ChEASUZ12-18974828-MESC-MOUSE
ChEANR3C1-23031785-PC12-MOUSE
ENCODE_TF_ChIP-seq_2015REST_HCT116_hg19
ENCODE_TF_ChIP-seq_2015REST_U-87 MG_hg19
ENCODE_TF_ChIP-seq_2015REST_Panc1_hg19

Top 10 significant databases (adj. value (Benjamini and Hochberg) < 0.05 and -score < −1.5) ordered by combined score (). For ChEA databases a PMID PubMed id is given after the TF. hg19 stays for human genome GRCh37.