BioMed Research International / 2015 / Article / Tab 1 / Research Article
Altered Spontaneous Brain Activity in Schizophrenia: A Meta-Analysis and a Large-Sample Study Table 1 The demographic and clinical data of studies included in the meta-analysis.
References Publication year Scanners Indices Patients age (years) Controls age (years) Patients (cases/F) Controls (cases/F) Diagnosis Duration of illness PANSS total PANSS positive PANSS negative Hoptman et al. [13 ] 2010 Siemens 1.5T ALFF/fALFF 36.5 ± 11.0 41.9 ± 10.9 29/3 26/7 CS 13.0 ± 7.2 (years) 76.5 ± 16.6 18.4 ± 6.2 20.2 ± 6.2 Huang et al. [14 ] 2010 GE 3T ALFF 24.2 ± 8.4 24.5 ± 8.6 66/36 66/36 FES 8.8 ± 14.1 (months) 107.2 ± 15.1 26.4 ± 5.2 20.7 ± 6.3 He et al. [15 ] 2013 GE 3T fALFF 25.4 ± 8.3 26.6 ± 8.9 104/55 104/54 FES 39.5 ± 31.9 (weeks) 92.1 ± 17.5 — — Ren et al. [16 ] 2013 GE 3T ALFF 24.3 ± 7.5 24.4 ± 7.6 100/59 100/59 FES 6.3 ± 11.0 (months) 97.9 ± 17.8 25.1 ± 6.0 18.8 ± 7.7 Turner et al. [17 ] 2013 Siemens/GE 3T ALFF/fALFF 34.4–44.8 34.4–42.5 146/35 160/46 CS 13.1–24.1 (years) 53.8–64.7 13.5–16.5 13.1–16.7 Yu et al. [18 ] 2014 Siemens 3T ALFF/fALFF 31.7 ± 9.6 29.9 ± 8.6 69/35 62/27 CS 7.1 ± 6.5 (years) 52.9 ± 16.8 12.1 ± 4.7 13.4 ± 6.1 Liu et al. [19 ] 2006 GE 1.5T ReHo 23.7 ± 4.4 24.4 ± 3.9 18/9 18/9 Mixed 26.8 ± 19.2 (months) 80.4 ± 18.7 — — Jiang et al. [20 ] 2010 GE 1.5T ReHo 16.4 ± 0.8 16.3 ± 0.9 18/9 18/9 EOS 9.6 ± 5.9 (months) 91.8 ± 6.7 — — Chen et al. [21 ] 2013 Siemens 3T ReHo 28.3 ± 1.43 35.7 ± 1.8 36/20 44/27 FES — 25.2 ± 6.9 — — Yu et al. [22 ] 2013 Siemens 3T ReHo 31.7 ± 9.6 29.9 ± 8.6 69/36 62/27 CS 7.1 ± 6.5 (years) 52.9 ± 16.8 12.1 ± 4.7 13.4 ± 6.1
Turner et al. [17 ] present the demographic information in 7 sites, respectively. Thus we only show the ranges of mean values from the 7 sites. All studies did not give the medication information except for the study of Hoptman et al. [13 ], so we did not list the information in the table. F, female; PANSS, Positive and Negative Syndrome Scale; FES, first-episode schizophrenia; CS, chronic schizophrenia; Mixed, FES and CS; EOS, early onset schizophrenia.