BioMed Research International / 2015 / Article / Tab 1

Research Article

Network Comparison of Inflammation in Colorectal Cancer and Alzheimer’s Disease

Table 1

Inflammation-associated genes common to both AD and CRC show opposite expression patterns. The 16 oppositely expressed common genes (in Figure 1(b)) between AD and CRC were assigned to inflammation-associated functional terms in IPA.

Functional categoryDownregulated in AD and upregulated in CRCUpregulated in AD and downregulated in CRC

ChemokinePTPN6, IRAK3, FLT3BAD, CD36

Inflammation relating to CRCDDIT3, FAS, IRF3

Inflammation relating to brainCCR6, CD28, DDIT3, FAS, FCER1G, NGFRPPARD

Cytokines relating to cancerCD28, FN1ABL1, EGFR

Cytokines relating to brainCD36

Genes detected in the CRC network from GSE4107 dataset.
Genes detected in the AD network from GSE1297 dataset.
#Genes detected in the AD network from GSE12685 dataset.

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