Biphasic Regulation of Lipid Metabolism: A Meta-Analysis of Icodextrin in Peritoneal Dialysis

Table 4

Effect of icodextrin use on lipid profiles (cross-sectional studies).

Factor	Number of studies	Heterogeneity test				Weighted mean difference
				value	Model of meta	Mean	[95% CI]	value
APO-B (mg/dL)	2	2.45	59.30%	0.117	R			0.855
Total cholesterol (mmol/L)	6	1.17	<0.01%	0.947	F			0.937
Triglycerides (mmol/L)	5	4.68	14.5%	0.322	F			0.001
HDL-C (mmol/L)	4	9.27	67.60%	0.026	R			0.223
LDL-C (mmol/L)	2	0.09	<0.01%	0.77	F			0.096
VLDL-C (mmol/L)	2	0.01	<0.01%	0.916	F			0.915

Note: the value was less than 0.05, and the WMD was considered statistically significant.
Model of meta: F: Fixed, R: Random.