Research Article

Biphasic Regulation of Lipid Metabolism: A Meta-Analysis of Icodextrin in Peritoneal Dialysis

Table 6

Effect of icodextrin on lipid profiles (in subgroups of diabetes).

FactorDiabetesNumber of studiesHeterogeneity testWeighted mean difference
valueModel of metaWMD[95% CI] value

Total cholesterol (mmol/L)Diabetes22.0551.20%0.152F0.087
Triglycerides (mmol/L)Diabetes20.49<0.01%0.483F0.467
HDL-C (mmol/L)Diabetes20.09<0.01%0.759F0.002
LDL-C (mmol/L)Diabetes21.4531.00%0.228F0.228

Note: the value was less than 0.05, and the WMD was considered statistically significant.