Resting-State fMRI in MS: General Concepts and Brief Overview of Its Application

Figure 1

Eleven resting-state networks identified by using independent component analysis (use of MELODIC tool by FMRIB Software Library toolbox, on a cohort of 20 healthy subjects, elaboration on our data) one sample t-test, (, family-wise corrected). Red shows positively correlated voxels and blue shows negatively correlated voxels. fMRI results are overlaid on the MNI152, 1 mm, standard brain. Images are shown according to the radiological convention. EC: executive control; SM: sensory-motor; lFP-rFP: left and right frontoparietal; DMN: default mode network; lV: lateral visual; mV: medial visual; CB: cerebellum; BG: basal ganglia.