ProSim: A Method for Prioritizing Disease Genes Based on Protein Proximity and Disease Similarity

<table class="figure-group"><tr class="fig-image" id="a"><td><object data="https://static.hindawi.com/articles/bmri/volume-2015/213750/figures/213750.fig.006a.svgz" name="213750.fig.006a" type="image/svg+xml"></object></td></tr><tr class="fig-caption"><td><b>(a) </b>Breast cancer</td></tr><tr class="fig-image" id="b"><td><object data="https://static.hindawi.com/articles/bmri/volume-2015/213750/figures/213750.fig.006b.svgz" name="213750.fig.006b" type="image/svg+xml"></object></td></tr><tr class="fig-caption"><td><b>(b) </b>Alzheimer disease</td></tr><tr class="fig-image" id="c"><td><object data="https://static.hindawi.com/articles/bmri/volume-2015/213750/figures/213750.fig.006c.svgz" name="213750.fig.006c" type="image/svg+xml"></object></td></tr><tr class="fig-caption"><td><b>(c) </b>Colorectal cancer</td></tr><tr class="fig-image" id="d"><td><object data="https://static.hindawi.com/articles/bmri/volume-2015/213750/figures/213750.fig.006d.svgz" name="213750.fig.006d" type="image/svg+xml"></object></td></tr><tr class="fig-caption"><td><b>(d) </b>Diabetes mellitus</td></tr><tr class="fig-image" id="e"><td><object data="https://static.hindawi.com/articles/bmri/volume-2015/213750/figures/213750.fig.006e.svgz" name="213750.fig.006e" type="image/svg+xml"></object></td></tr><tr class="fig-caption"><td><b>(e) </b>Lung cancer</td></tr><tr class="fig-image" id="f"><td><object data="https://static.hindawi.com/articles/bmri/volume-2015/213750/figures/213750.fig.006f.svgz" name="213750.fig.006f" type="image/svg+xml"></object></td></tr><tr class="fig-caption"><td><b>(f) </b>Prostate cancer</td></tr></table>

<div>Tenfold cross validation for true disease gene prediction: (a) breast cancer, (b) Alzheimer disease, (c) colorectal cancer, (d) diabetes mellitus, (e) lung cancer, and (f) prostate cancer.</div>

BioMed Research International

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Figure 6

Figure 6: ProSim: A Method for Prioritizing Disease Genes Based on Protein Proximity and Disease Similarity 