TY - JOUR A2 - Ide, Takeshi AU - García-Porta, Nery AU - Rico-del-Viejo, Laura AU - Ferreira-Neves, Helena AU - Peixoto-de-Matos, Sofia C. AU - Queirós, Antonio AU - González-Méijome, José M. PY - 2015 DA - 2015/03/31 TI - Performance of Three Multipurpose Disinfecting Solutions with a Silicone Hydrogel Contact Lens SP - 216932 VL - 2015 AB - Purpose. To evaluate the clinical performance of a silicone hydrogel (Si-Hy) soft contact lens (CL) in combination with three different multipurpose disinfecting solutions (MPDSs). Methods. This was a prospective, randomized, single-masked, crossover, and comparative study in which 31 habitual soft CL wearers were randomly assigned to one of the three MPDSs (Synergi, COMPLETE RevitaLens, and OPTI-FREE PureMoist) for 1 month with a 1-week wash-out period between each exposure. All subjects were successfully refitted with a Si-Hy CL (Biofinity). Subjects were then scheduled for follow-up visits after 1 month of lens wear, being evaluated at 2 and 8 hours after lens insertion. Visual Analogue Scales (VAS) were used to gauge comfort rating. Results. The tarsal conjunctiva showed a significantly different degree of lid redness between the MPDSs at the 2-hour visit (P<0.05, Kruskal-Wallis test), being lower for COMPLETE RevitaLens compared to the other two MPDSs (Mann-Whitney U test). Furthermore, a significantly different degree of lid roughness at the 8-hour visit was seen (P<0.05, Kruskal-Wallis test), being higher for Synergi (Mann-Whitney U test). The subjective comfort was similar with the three MPDSs. Conclusion. Tarsal conjunctival response should be also considered in the context of the clinical performance of MPDs at the ocular surface. SN - 2314-6133 UR - https://doi.org/10.1155/2015/216932 DO - 10.1155/2015/216932 JF - BioMed Research International PB - Hindawi Publishing Corporation KW - ER -