Pim-2/mTORC1 Pathway Shapes Inflammatory Capacity in Rheumatoid Arthritis Synovial Cells Exposed to Lipid Peroxidations

Figure 2

4-HNE activates Pim-2 kinase signaling in MH7A synovial cells. (a-b) Western blots and histograms showing the increased Pim-2 kinase protein levels by 4-HNE treatment in MH7A synovial cells. (c) Histograms showing that the increased Pim-2 kinase mRNA levels by 4-HNE treatment in MH7A synovial cells. Results are averages of three independent experiments. Data represent mean ± SEM. and .

(a)

(b)

(c)