Pim-2/mTORC1 Pathway Shapes Inflammatory Capacity in Rheumatoid Arthritis Synovial Cells Exposed to Lipid Peroxidations

<div>Pim-2 kinase overexpression may partly activate mTORC1 pathway under HNE conditions. (a-b) Western blots and histograms showing that Pim-2 overexpression activated mTORC1 activity (indicated by pp70S6K/p70S6K and p4EBP1/4EBP1) under basal and 4-HNE conditions. Results are averages of three independent experiments. 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BioMed Research International

fig3

Figure 3

Figure 3: Pim-2/mTORC1 Pathway Shapes Inflammatory Capacity in Rheumatoid Arthritis Synovial Cells Exposed to Lipid Peroxidations 