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BioMed Research International
Volume 2015, Article ID 242437, 14 pages
http://dx.doi.org/10.1155/2015/242437
Review Article

Prognostic Indications of Elevated MCT4 and CD147 across Cancer Types: A Meta-Analysis

1Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
2Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA
3Department of Medical Oncology, Thomas Jefferson University, Philadelphia, PA 19107, USA
4Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA
5Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA
6Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, PA 19107, USA

Received 16 August 2015; Revised 13 October 2015; Accepted 18 October 2015

Academic Editor: Sumanta Chatterjee

Copyright © 2015 Cory D. Bovenzi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Data obtained via univariate analysis concerning MCT1, MCT4, and CD147 expression patterns in relation to overall and disease-free survival. This information is presented separately since only data obtained via multivariate analysis have been included in the Forest Plot meta-analyses.

Supplementary Table 1: Elevated MCT4 expression is associated with decreased overall survival: studies without multivariate analysis provided (HCC: hepatocellular carcinoma, TACE: transarterial chemoembolization, ACC: adenoid cystic carcinoma, SCC: squamous cell carcinoma, TNBC: triple-negative breast cancer, and NSCLC: non-small cell lung cancer).

Supplementary Table 2: Elevated MCT4 expression is associated with decreased disease-free survival: studies without multivariate analysis provided (CA: carcinoma).

Supplementary Table 3: Elevated CD147 expression is associated with decreased overall survival: studies without multivariate analysis provided.

Supplementary Table 4: Elevated CD147 expression is associated with decreased disease-free survival: studies without multivariate analysis provided.

Supplementary Table 5: MCT1 expression is not associated with prognosis: studies without multivariate analysis provided (OS: overall survival and DFS: disease-free survival).

  1. Supplementary Material