Poorly Understood Aspects of Striated Muscle Contraction

Figure 5

Model of the Huxley and Simmons type [47]. Force development is assumed to occur by thermally excited swing of a myosin head subdomain that stretches an independent elastic element. The swing is forward-biased (producing a power stroke) by progressively increased binding affinity between the myosin head and actin for each transition (to the right) that stretches the elastic element.