Acupuncture May Exert Its Therapeutic Effect through MicroRNA-339/Sirt2/NFB/FOXO1 Axis
MiRNA-339 increased the acetylated NF-κB and FOXO1 expression level. Overexpression of miRNA-339 significantly increased the acetylated NF-κB (a) and FOXO1 (b) level in a time-dependent manner. SH-SY5Y cells were treated with miRNA-339 mimic at 50 nM for 24 and 48 h. At each time point, the cell lysates were collected for western blotting. , versus control.