Research Article

Administration of 4-(α-L-Rhamnosyloxy)-benzyl Isothiocyanate Delays Disease Phenotype in SOD1G93A Rats: A Transgenic Model of Amyotrophic Lateral Sclerosis

Figure 8

iNOS formation and MMP-9 expression. Immunohistochemical (IHC) detection of iNOS tissue expression reveals that untreated SOD1tg rats have a positive staining for this marker (a), while there is an absence of positivity in brain sections sampled from GMG-ITC treated SOD1tg rats (b). By IHC stain, brain sections sampled from untreated SOD1tg rats exhibit positive staining for MMP-9 (c), whereas brain sections obtained from GMG-ITC treated SOD1tg rats do not stain for MMP-9 (d).
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