Thymoquinone-Loaded Nanostructured Lipid Carrier Exhibited Cytotoxicity towards Breast Cancer Cell Lines (MDA-MB-231 and MCF-7) and Cervical Cancer Cell Lines (HeLa and SiHa)

Table 1

Physicochemical characteristics of NLCs and TQ-NLCs after synthesis.

Formulation	Duration of storage (week)	Average diameter (nm)	Polydispersity index (PDI)	Zeta potential; (mV)
NLC	0	31.25 ± 0.1793^a	0.161 ± 0.0043^1	19.68 ± 0.5189^α
	24	33.11 ± 0.3398^b	0.172 ± 0.0061^1,2	16.25 ± 0.7920^β,γ
TQ-NLC	0	35.66 ± 0.1235^*c	0.177 ± 0.0024^*2	16.72 ± 0.4474^*β
	24	37.05 ± 0.2742^*d	0.211 ± 0.0043^*3	14.78 ± 0.2470^*γ

Values were the means of three replicate samples. The data were presented as mean ± SEM. * were significant as compared to NLC while a, b, c, d, 1, 2, 3, , , and were significantly different ().