Research Article

Sevoflurane Induces DNA Damage Whereas Isoflurane Leads to Higher Antioxidative Status in Anesthetized Rats

Table 1

Hemodynamic variables in anesthetized rats with 2% isoflurane or 4% sevoflurane (ISO and SEVO, resp.). Data were recorded at 30 (), 60 (), 90 (), and 120 min () of anesthesia. Data are presented as mean (S.D.). HR: heart rate; SAP: systolic arterial pressure; MAP: mean arterial pressure; DAP: diastolic arterial pressure. among time points in the same group and between groups regarding a specific time point.

VariablesGroupsTime points

Heart rate (beats/min)ISO 312 (30)326 (30)327 (44)324 (46)
SEVO 323 (45) 338 (32) 357 (26) 365 (29)

SAP (mm Hg)ISO 87 (13) 90 (9) 87 (14) 86 (16)
SEVO 103 (19) 98 (15) 98 (12) 105 (18)

MAP (mm Hg)ISO 78 (9) 84 (6) 80 (9) 79 (12)
SEVO 89 (21) 84 (17) 84 (12) 87 (17)

DAP (mm Hg)ISO 67 (10) 73 (7) 73 (5) 65 (11)
SEVO 76 (20) 70 (15) 71 (11) 74 (15)