Iron Dextran Increases Hepatic Oxidative Stress and Alters Expression of Genes Related to Lipid Metabolism Contributing to Hyperlipidaemia in Murine Model
Levels of gene expression in the liver of rats offered a standard diet (S) and rats that received injections of iron dextran (SI). Values are the mean ± standard deviation (). (a) Levels of relative srebp-2 (sterol regulatory element-binding proteins-2)/18S expression. (b) Levels of relative HMG-CoA reductase/18S expression. (c) Levels of relative LDL receptor/18S expression. (d) Levels of relative ApoB100 (apolipoprotein B-100)/18S expression. (e) Levels of relative PPAR alpha (peroxisome proliferator-activated receptor alpha)/18S expression. (f) Levels of relative cpt1a (carnitine palmitoyltransferase 1)/18S expression. (g) Levels of relative L-FABP (liver fatty acid binding protein)/18S expression. (h) Levels of relative MTP (microsomal triglyceride transfer protein)/18S expression. with respect to the S group (student’s t-test).