Comparative Effectiveness of Tocilizumab and TNF Inhibitors in Rheumatoid Arthritis Patients: Data from the Rheumatic Diseases Portuguese Register, Reuma.pt

Figure 2

Remission (a) and EULAR response rate (b) at 6 months stratified by previous biologic therapy. (a) Biologic-naïve patients treated with TCZ had significantly higher rates of DAS28, CDAI, and SDAI remission, with nonsignificant differences in the more stringent Boolean remission. TCZ-treated patients previously exposed to at least 1 biologic had greater frequencies of DAS28 remission than those treated with TNFi, with similar rates of CDAI, SDAI, and Boolean remission. (b) EULAR response rates were significantly higher in the TCZ group for both previous biologic statuses, although the differences were greater in biologic-naïve patients. value significant at <0.05.

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