The Combinational Polymorphisms of ORAI1 Gene Are Associated with Preventive Models of Breast Cancer in the Taiwanese

Table 3

Estimated joint effects on models of 2- to 5-SNP combinations associated with breast cancer.

Combined SNP number; (specific SNP combination)^*1	SNP; genotypes	Case number; /control number	OR	95% CI	value	Power
2-SNP	Others	330/261	1		0.005^*2	0.792
(1-2)	1-1	15/29	0.409	0.215–0.779
3-SNP	Others	330/261	1		0.005^*2	0.792
(1-2-5)	1-1-2	15/29	0.409	0.215–0.779
4-SNP	Others	330/261	1		0.005^*2	0.792
(1-2-3-5)	1-1-2-2	15/29	0.409	0.215–0.779
5-SNP	Others	330/262	1		0.008^*2	0.750
(1-2-3-4-5)	1-1-2-1-2	15/28	0.425	0.223–0.813

The information of the SNP and genotypes is provided in Table 1.
^*2The models have significance on the occurrence of breast cancer (P < 0.05).
OR = odds ratio.