Zearalenone Inhibits Rat and Human 11β-Hydroxysteroid Dehydrogenase Type 2

Figure 5

The mode of action of zearalenone (ZEN) on human 11β-hydroxysteroid dehydrogenase isoform 2 (HSD11B2). The HSD11B2 activity was analyzed using different concentrations of cortisol. (a) Michaelis-Menten kinetics; (b) Lineweaver-Burk plots. Graph includes results from four separate and independent experiments.

(a)

(b)