Omega-3 PUFAs Lower the Propensity for Arachidonic Acid Cascade Overreactions

Figure 1

Balancing prostaglandin formation and action. The prostaglandin part of the arachidonic acid cascade begins with a stimulated phospholipase A2 releasing precursor HUFA from membrane phospholipids. The relative intensity of reaction for n-3 and n-6 mediators is shown as a ratio next to the interacting enzyme or receptor.