The 482Ser of PPARGC1A and 12Pro of PPARG2 Alleles Are Associated with Reduction of Metabolic Risk Factors Even Obesity in a Mexican-Mestizo Population

Figure 2

Metabolic markers, adipokines, and body dimensions and distribution of body fat storage measurements in obese subjects by genotypes and phenotypes. (a), (b), (c) and (d) PPARGC1A Gly482Ser polymorphism; (e) and (f) Pro12Ala in PPARG2. One way ANOVA test with Tukey’s post hoc test, and Student’s  -test. Polymorphism PPARGC1A: phenotype Gly− (Genotype 482Ser/Ser) and, phenotype Gly+ (genotypes 482Gly/Ser plus 482Gly/Gly). Polymorphism PPARG2: phenotype Ala+ (genotypes 12Pro/Ala plus 12Ala/Ala) and phenotype Ala− (genotype 12Pro/Pro). Data are means ± SD. .

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