Review Article

Effectiveness and Safety of Controlled Venous Pressure in Liver Surgery: A Systematic Review and Network Meta-Analysis

Table 1

Characteristics of included studies.

StudyCountryCase (T/C, )Age (T/C, y)Sex (M/F)InterventionBaseline CVP (T/C)SurgeryDiagnosis
T  C

Otsubo et al. 2004 [13]Japan47/5659.3 ± 14.4/55.4 ± 16.130/1741/15IVCC/control10.6 ± 2.6/10.1 ± 2.8HepatectomyHepatocarcinoma (28/31), metastatic tumor (10/14), cholangiocellular carcinoma (5/4), others (4/7)

Chen et al. 2006 [14]China60/5839.7 ± 3.6/41.5 ± 4.153/751/7IVCC/control7.6 ± 3.0/7.7 ± 2.4HepatectomyHBV related cirrhosis (51/54), HCV related cirrhosis (6/4), others (1/2)

Wang et al. 2006 [15]China25/2545.3 ± 14.6/46.0 ± 12.119/621/4IAC/controlHepatectomyLiver cirrhosis (14/15), others (11/10)

Kato et al. 2008 [16]Japan43/4265 (28–82)/67 (38–79)IVCC/control7 (3–14)/7 (2–16)Liver resectionHepatocarcinoma (35/34), metastatic tumor (6/7), cholangiocellular (1/0)

Liu et al. 2008 [17]China23/2345.4 ± 13.0/42.9 ± 12.614/916/7IAC/control2.7–5.4Liver resectionHepatocarcinoma (23/23)

Uchiyama et al. 2009 [18]Japan20/5861.6 ± 12.9/64.8 ± 16.815/544/14IVCC/controlHepatectomyHepatocarcinoma (9/31), metastatic tumor (6/20), others (5/7)

Feng et al. 2010 [19]China43/4348 ± 10/47 ± 126/378/35IAC/control10 (6–12)/10 (6–11)TransplantationHepatocirrhosis (15/16), severe hepatitis (7/8), carcinoma (19/17), others (2/2)

Liu et al. 2010 [20]China67/8351 (33–69)/55 (14–76)48/3555/12IVCC/control7.8 ± 3.5/8.3 ± 3.6Liver lobectomyPrimary liver carcinoma (67/83)

Rahbari et al. 2011 [21]Germany65/6357.2 ± 10.9/59.2 ± 12.137/2842/21IVCC/IAC9.2 ± 3.6/7.6 ± 3.6Liver resectionHepatocarcinoma (19/20), metastatic tumor (35/37), others (11/6)

Zhu et al. 2012 [22]China96/96IVCC/IAC10.5 ± 1.3/10.8 ± 1.2Liver resectionLiver tumors (96/96)

Yang et al. 2013 [23]China60/5348.7 ± 10.8/49.5 ± 12.143/1738/15IVCC/control7.6 ± 3.2/—HepatectomyHepatocarcinoma (31/26), metastatic tumor (7/7), others (22/20)

Ryu et al. 2010 [24]South Korea19/1929 ± 11/26 ± 915/318/1IAC/control8.5/7.5Liver lobectomyDonors (19/19)

Wang et al. 2013 [25]China33/3237.1 ± 10.1/35.9 ± 10.326/726/6IAC/controlLiver lobectomyHepatocarcinoma (11/18), hepatocirrhosis (16/12), hepatitis B (4/1), others (2/1)

IVCC: infrahepatic inferior vena cava clamping; IAC: low central vein pressure by intraoperative anesthetic control; T: treatment group; C: control group.
Data were presented as median (range).