Vitamin K1 Exerts Antiproliferative Effects and Induces Apoptosis in Three Differently Graded Human Colon Cancer Cell Lines

Figure 8

Ornithine decarboxylase (ODC) activity of Caco-2, HT-29, and SW480 cell lines in response to vitamin K1 (VK1) treatment. Effects of increasing concentrations of VK1 (10 μM, 50 μM, 100 μM, and 200 μM) on the ODC activity in Caco-2 (a), HT-29 (b), and SW480 (c) cell lines after 24 h, 48 h, and 72 h of treatment. All data represent the result of three different experiments (mean ± SEM). For each time of treatment, data were analyzed by Kruskal-Wallis analysis of variance and Dunn’s multiple comparison test. ^* compared to control cells.

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