Functional Relevance of Coronary Artery Disease by Cardiac Magnetic Resonance and Cardiac Computed Tomography: Myocardial Perfusion and Fractional Flow Reserve

Table 1

Summary of the most common drug stressors used for the evaluation of myocardial perfusion.

Drug stressors	Action	Half-life	Side effects	Cost
Adenosine	Coronary vasodilatation induced by not-selective A1 adenosine-receptors stimulation (increasing cellular cAMP levels)	10 seconds	Facial flushing; Diaphoresis nausea asthma; Bradyarrhythmias
Dipyridamole	Coronary vasodilatation induced by inhibition of the phosphodiesterase enzymes that normally break down cAMP (increasing cellular cAMP levels)	25 minutes	Facial flushing; Diaphoresis nausea asthma; Bradyarrhythmias
Regadenoson	Coronary vasodilatation induced by selective A2A adenosine-receptors stimulation	2-3 minutes	Headache, dizziness, nausea, stomach discomfort, decreased sense of taste, mild chest discomfort, or warmth, redness, or tingly feeling under your skin