Research Article
Low Mutational Burden of Eight Genes Involved in the MAPK/ERK, PI3K/AKT, and GNAQ/11 Pathways in Female Genital Tract Primary Melanomas
Table 2
Molecular characterization of the eight genes in the 16 female genital tract primary melanomas.
| | Gene | Location | Number of mutations | % |
| | BRAF | Exon 15, V600E | 1 | 6.2% |
| | NRAS | Exon 2, codons 12-13 | 0 | 0% | | Exon 3, codon 61 | 0 | 0% |
| | HRAS | Exon 2, codons 12-13 | 0 | 0% | | Exon 3, codon 61 | 0 | 0% |
| | KRAS | Exon 2, codons 12-13 | 0 | 0% | | Exon 3, codon 61 | 0 | 0% |
| | cKIT | Exon 11 | 0 | 0% | | Exon 13 | 0 | 0% | | Exon 17 | 0 | 0% | | Exon 18 | 0 | 0% |
| | PI3K | Exon 9 | 0 | 0% | | Exon 20 | 0 | 0% |
| | GNAQ | Exon 4, R183 | 0 | 0% | | Exon 5, Q209 | 0 | 0% |
| | GNA11 | Exon 4, R183 | 0 | 0% | | Exon 5, Q209 | 0 | 0% |
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