Research Article

Mineral and Skeletal Homeostasis Influence the Manner of Bone Loss in Metabolic Osteoporosis due to Calcium-Deprived Diet in Different Sites of Rat Vertebra and Femur

Table 2

Static histomorphometric parameters of trabecular bone in L5 vertebral body sections.

GroupBV/TV (%)Tb.Th (µm)Tb.N (/mm)Tb.Sp (µm)

124.54 ± 2.2859.56 ± 3.144.14 ± 0.54185.12 ± 28.70
223.35 ± 2.3153.29 ± 2.284.39 ± 0.52180.33 ± 26.25
314.97 ± 3.5550.75 ± 6.502.93 ± 0.41298.79 ± 53.81
414.36 ± 0.7347.07 ± 2.123.03 ± 0.06285.34 ± 11.12

All values are expressed as mean ± sd, ANOVA followed by Bonferroni’s test: < 0.05, < 0.01 versus Group 1; < 0.001 versus Group 2. Group 1: baseline; Group 2: control, normal diet; Group 3: calcium-deprived diet for 4 weeks; Group 4: calcium-deprived diet, plus concomitant administration of PTH (1-34) 40 µg/kg/day, for 4 weeks.