Research Article

Mineral and Skeletal Homeostasis Influence the Manner of Bone Loss in Metabolic Osteoporosis due to Calcium-Deprived Diet in Different Sites of Rat Vertebra and Femur

Table 3

Static histomorphometric parameters of cortical bone in L5 vertebral body sections.

GroupAnterolateral Ct.ThPosterior Ct.Th

1311.84 ± 71.47176.15 ± 33.10
2321.49 ± 35.97168.85 ± 26.67
3197.84 ± 9.54148.23 ± 35.69
4162.67 ± 10.53130.37 ± 13.37

All values (µm) are expressed as mean ± sd, ANOVA followed by Bonferroni’s test: < 0.001 versus Group 1; < 0.001 versus Group 2. Group 1: baseline; Group 2: control, normal diet; Group 3: calcium-deprived diet for 4 weeks; Group 4: calcium-deprived diet, plus concomitant administration of PTH (1-34) 40 µg/kg/day, for 4 weeks.