Mineral and Skeletal Homeostasis Influence the Manner of Bone Loss in Metabolic Osteoporosis due to Calcium-Deprived Diet in Different Sites of Rat Vertebra and Femur

Table 5

Static histomorphometric parameters in middiaphyseal femoral sections.

Group	Round-shaped sections			Sharp-edge-shaped sections
	Total cross section area	Cortical bone area	Medullary canal area	Total cross section area	Cortical bone area	Medullary canal area
1	11.07 ± 0.61	6.61 ± 0.44	4.36 ± 0.57	10.94 ± 0.50	6.74 ± 0.48	4.19 ± 0.55
2	12.19 ± 1.38	7.35 ± 0.84	4.83 ± 0.54	12.43 ± 1.50	7.73 ± 0.88	4.70 ± 0.53
3	12.71 ± 0.75	6.90 ± 0.48	5.64 ± 0.38	12.97 ± 0.87	7.25 ± 0.68	5.67 ± 0.32
4	11.71 ± 0.78	6.50 ± 0.35	5.17 ± 0.49	12.20 ± 0.89	6.67 ± 0.45	5.50 ± 0.46

All values (mm²) are expressed as mean ± sd, ANOVA followed by Bonferroni’s test: < 0.05 versus Group 1; < 0.05 versus Group 2. Group 1: baseline; Group 2: control, normal diet; Group 3: calcium-deprived diet for 4 weeks; Group 4: calcium-deprived diet, plus concomitant administration of PTH (1-34) 40 µg/kg/day, for 4 weeks.