Mineral and Skeletal Homeostasis Influence the Manner of Bone Loss in Metabolic Osteoporosis due to Calcium-Deprived Diet in Different Sites of Rat Vertebra and Femur

Table 7

Static histomorphometric parameters in distal metaphyseal femoral sections.

Group	BV/TV (%)	Tb.Th (µm)	Tb.N (/mm)	Tb.Sp (µm)	Ct-B-Ar (mm^2)
1	18.26 ± 7.36	51.63 ± 10.19	3.16 ± 0.67	255.36 ± 104.87	6.01 ± 0.41
2	17.76 ± 4.78	50.36 ± 7.92	3.49 ± 0.51	241.08 ± 49.04	5.93 ± 0.70
3	6.94 ± 1.47	42.88 ± 5.01	1.62 ± 0.40	601.63 ± 165.23	5.71 ± 0.19
4	7.50 ± 2.05	43.89 ± 8.01	1.65 ± 0.19	564.60 ± 84.57	5.91 ± 0.60

All values are expressed as mean ± sd, ANOVA followed by Bonferroni’s test: < 0.05, < 0.01 versus Group 1; < 0.05, < 0.01, and < 0.001 versus Group 2. Group 1: baseline; Group 2: control, normal diet; Group 3: calcium-deprived diet for 4 weeks; Group 4: calcium-deprived diet, plus concomitant administration of PTH (1-34) 40 µg/kg/day, for 4 weeks.