Pretreatment Diffusion-Weighted MRI Can Predict the Response to Neoadjuvant Chemotherapy in Patients with Nasopharyngeal Carcinoma

Figure 2

DW MRI findings in a 48-year-old female patient with NPC who responded to neoadjuvant chemotherapy. Pretreatment (a) axial contrast-enhanced T1-weighted image and (b) ADC maps showing an enlarged lymph node in the left retropharyngeal space (arrow). The mean pretreatment ADC of this lesion was 0.993 × 10⁻³ mm²/sec. Posttreatment (c) axial contrast-enhanced T1-weighted image and (d) ADC maps showing that the formerly enlarged right lymph node partially resolved; the volume of this lesion reduced by 83%. Neoadjuvant chemotherapy increased the mean ADC of this lesion to 1.383 × 10⁻³ mm²/sec.

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