Characterization of Multidrug Resistant Extended-Spectrum Beta-Lactamase-Producing Escherichia coli among Uropathogens of Pediatrics in North of Iran

Table 2

Percentage of antimicrobial susceptibility in ESBL-producing E. coli strains based on MIC results.

Antimicrobial agents	(%)	(%)	(%)	CLSI breakpoints; (g/mL)
				Cephalosporins
Cefepime	67	13	20	≤8	≥32
Cefixime	99	0	1	≤0.25	≥1
Ceftriaxone	28	42	30	≤8	≥64
Ceftazidime	19	26	55	≤16	≥32
Ceftizoxime	46	27	27	≤8	≥64
Cefotaxime	13	40	47	≤8	≥64
Carbapenems
Imipenem	23	11	66	≤4	≥16
Meropenem	18	15	67	≤4	≥16
Aminoglycosides
Amikacin	34	8	58	≤16	≥64
Gentamicin	37	12	51	≤4	≥16
Others
Ciprofloxacin	76	0	24	≤1	≥4
Colistin	82	0	18	≤2	≥4
Trimethoprim/sulfamethoxazole	65	7	28	≤2/38	≥4/76
Piperacillin/tazobactam	20	38	42	≤16/4	≥128/4

: resistance, : intermediate, : sensitive, CLSI: Clinical Laboratory Standards Institute, and ESBL: extended-spectrum beta-lactamase.