In Vitro and In Vivo Evaluation of Vancomycin-Loaded PMMA Cement in Combination with Ultrasound and Microbubbles-Mediated Ultrasound

<div>Schematic drawings of (a) the placement of the cement specimens in the tibia of a rabbit and (b) the design of the in vivo study. VAN: vancomycin; MBs: microbubbles; US: ultrasound; CFU: colony-forming units. Black arrow: bone cement; red arrow: 1-mm-diameter hole.</div>

BioMed Research International

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Figure 1

Figure 1: In Vitro and In Vivo Evaluation of Vancomycin-Loaded PMMA Cement in Combination with Ultrasound and Microbubbles-Mediated Ultrasound 