Review Article

Effectiveness of Hyaluronic Acid Administration in Treating Adhesive Capsulitis of the Shoulder: A Systematic Review of Randomized Controlled Trials

Table 2

Characteristics of the included trials.

AuthorYearDiagnostic toolsMean age (years)Gender (M/F)Duration of symptoms (months)InterventionTotal number of HA injection dosesInjection guidanceInjection site

Rovetta and Monteforte [21]199830History + PE + US64.29/218.3() HA + CS + PT: 20 mg HA + 20 mg triamcinolone + PT (4–12 weeks)
() CS + PT: 20 mg triamcinolone + PT (4–12 weeks)
8 (15-day intervals in the first month and then monthly for 6 months)Anatomy (posterior approach)IA

Calis et al. [12]200690 (95 shoulders)History + PE57.033/57>1() HA: 30 mg HA
() CS: 40 mg triamcinolone
() PT: 10 days
() Home exercises
2 (weekly)Anatomy (posterior approach)IA

Hsieh et al. [13]201263History + PE54.520/434.5() HA + PT: 20 mg HA + PT (12 weeks)
() PT: 12 weeks
3 (weekly)Anatomy (posterior approach)IA

Park et al. [22]201390History + PE + US55.822/685.3() HA: HA 20 mg + lidocaine (18 mL)
() CS: triamcinolone 40 mg + lidocaine (4 mL)
3 (every 2 weeks)US (posterior approach)IA

CS: corticosteroid; F: female; HA: hyaluronic acid; IA: intra-articular; M: male; PE: physical examination; PT: physical therapy; US: ultrasonography.