BioMed Research International

BioMed Research International / 2015 / Article

Corrigendum | Open Access

Volume 2015 |Article ID 314651 | https://doi.org/10.1155/2015/314651

Helle Høyer, Geir J. Braathen, Øyvind L. Busk, Øystein L. Holla, Marit Svendsen, Hilde T. Hilmarsen, Linda Strand, Camilla F. Skjelbred, Michael B. Russell, "Corrigendum to “Genetic Diagnosis of Charcot-Marie-Tooth Disease in a Population by Next-Generation Sequencing”", BioMed Research International, vol. 2015, Article ID 314651, 2 pages, 2015. https://doi.org/10.1155/2015/314651

Corrigendum to “Genetic Diagnosis of Charcot-Marie-Tooth Disease in a Population by Next-Generation Sequencing”

Received08 Sep 2015
Accepted21 Sep 2015
Published08 Oct 2015

In Table and Supplemental Table of the published paper entitled “Genetic Diagnosis of Charcot-Marie-Tooth Disease in a Population by Next-Generation Sequencing” [1], we classified two variants as likely pathogenic. These two variants (NM_001126131.1:c.[1491G>C(;)2243G>C]), identified in the POLG gene, were carried by one patient (ID 62). As it was not possible to examine whether the two variants were in cis or trans, that is, situated on the same or different alleles, these two variants should have been reported as uncertain pathogenic variants.

This change also influences the Results, where the prevalence of identified variants is corrected to 8 likely and 17 uncertain pathogenic variants.

In Figure , the number of families with likely pathogenic variants is reduced to   (9%) and the number for families with uncertain pathogenic variants is increased to   (12%). And in Figure (b), the number of CMT2 families in the category “other point mutations” is reduced to   (21%) and the number of families with uncertain pathogenic variants is increased to   (15%). See corrected Figures 1 and 2(b).

References

  1. H. Høyer, G. J. Braathen, Ø. L. Busk et al., “Genetic diagnosis of Charcot-Marie-Tooth disease in a population by next-generation sequencing,” BioMed Research International, vol. 2014, Article ID 210401, 13 pages, 2014. View at: Publisher Site | Google Scholar

Copyright © 2015 Helle Høyer et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


More related articles

790 Views | 258 Downloads | 1 Citation
 PDF Download Citation Citation
 Download other formatsMore
 Order printed copiesOrder

Related articles

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.