Table 4: Results of confirmatory association analysis between the rs2498794 SNP and smoking or cancer-related phenotypes.

SNP StagePvalues for confirmatory and combined association analyses in genotypic/dominant/recessive models for each minor allele
Cancer status (present illness)Cancer status (present or past illnesses)Smoking historySmoking period (year)CPDaBrinkman (smoking) index

rs2498794confirmatory0.208/0.453/0.0770.075/0.903/0.0380.552/0.892/0.3360.143/0.743/0.0920.912/0.890/0.7440.141/0.733/0.092
rs2498794combined0.910/0.665/0.8900.205/0.482/0.1900.901/0.824/0.7630.068/0.641/0.0480.610/0.529/0.6100.073/0.486/0.070

Cigarettes smoked per day.
Significant association between the minor T allele of the SNP and noncancer status (present or past illness) in the recessive model ().
Significant association between the minor T allele of the SNP and longer periods of smoking history in the recessive model ().