Molecular PET Imaging of Cyclophosphamide Induced Apoptosis with ¹⁸F-ML-8

Table 2

Biodistribution of ¹⁸F-ML-8 in normal mice after intravenous injection.

Organ	5 min	30 min	60 min	120 min
Blood	7.41 ± 2.29	2.89 ± 0.61	1.04 ± 0.16	0.23 ± 0.10
Brain	0.34 ± 0.07	0.23 ± 0.14	0.10 ± 0.02	0.07 ± 0.04
Heart	4.27 ± 0.33	1.39 ± 0.35	0.64 ± 0.26	0.15 ± 0.07
Lung	5.61 ± 1.08	1.63 ± 0.41	0.77 ± 0.21	0.41 ± 0.17
Liver	3.80 ± 1.08	1.96 ± 0.37	1.21 ± 0.14	0.25 ± 0.07
Pancreas	2.98 ± 1.18	0.80 ± 0.25	0.47 ± 0.12	0.24 ± 0.10
Kidney	24.5 ± 4.31	7.10 ± 2.20	3.29 ± 1.12	0.59 ± 0.25
Spleen	3.22 ± 0.60	1.01 ± 0.25	0.38 ± 0.15	0.21 ± 0.12
Intestine	3.04 ± 0.27	1.06 ± 0.24	0.41 ± 0.07	0.21 ± 0.05
Muscle	2.68 ± 0.48	1.05 ± 0.11	0.39 ± 0.12	0.15 ± 0.06
Stomach	2.25 ± 0.26	0.81 ± 0.31	0.40 ± 0.19	0.19 ± 0.05
Bone	7.75 ± 1.99	7.57 ± 2.21	6.71 ± 1.50	5.62 ± 0.77

Note: data are mean % ID/g ± SD (n = 5).