OSM Enhances Angiogenesis and Improves Cardiac Function after Myocardial Infarction
OSM treatment attenuated cardiomyocyte apoptosis after MI. (a) Representative digital micrographs showing cardiomyocyte apoptosis in the border zone of all groups of mice. Bar: 25 μm. (b) Western blot assay of cleaved caspase 3 and caspase 3 in the border zone of the six groups of mice. (c) Quantitative analysis of cardiomyocyte apoptosis after MI in counts/high-power field (HPF). (d) Quantitative data of the expression of cleaved caspase 3 in the six groups of mice. The values are means ± SD. versus WT group, versus WT + MI group, and versus Oβ−/−S group. in each group.