Single Nucleotide Polymorphisms of the GJB2 and GJB6 Genes Are Associated with Autosomal Recessive Nonsyndromic Hearing Loss

Table 5

Comparative analysis between minor allele frequency described in the database and minor allele frequency in the whole study group.

Gene	SNP ID; (nucleotide change)	MAF ref	MAF study	value; (ref × study)
GJB2	rs3751385 (C/T)	T = 0.360	0.405	0.513
	rs7994748 C/T	C = 0.481	0.173
	rs7329857 C/T	T = 0.079	0.043	0.287
	rs7987302 G/A	A = 0.098	0.026	0.035
GJB6	rs7322538 G/A	A = 0.214	0.114	0.056
	rs9315400 C/T	T = 0.362	0.451	0.200
	rs877098 C/T	T = 0.429	0.486	0.418
	rs945369 A/C	C = 0.352	0.400	0.472
	rs7333214 T/G	T = 0.302	0.236	0.293

MAF (ref) ≥0.05: minor allele frequency information from public database, NCBI dbSNP Build 132; MAF (study): minor allele frequency in the whole study group. Significant values are shown in boldface.