A Comprehensive Systems Biological Study of Autophagy-Apoptosis Crosstalk during Endoplasmic Reticulum Stress

<div>The time course profile of cell treatment with respect to low and high levels of TM. HepG2 cells were treated with (left panel) low (1 <i>μ</i>M) and (right panel) high (100 <i>μ</i>M) level of TM. (a) The autophagy (LC3II, p62) and apoptosis markers (procaspase-3, cleaved PARP) were followed in time by immunoblotting. (b) The percentage of apoptotic cells was calculated by Annexin-V-FLUOS kit (errors bars represent standard deviation).</div>

BioMed Research International

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Figure 2

Figure 2: A Comprehensive Systems Biological Study of Autophagy-Apoptosis Crosstalk during Endoplasmic Reticulum Stress 