Review Article

CCAAT/Enhancer Binding Protein β in relation to ER Stress, Inflammation, and Metabolic Disturbances

Table 1

Regulatory factors for C/EBP-β production, C/EBP-β target genes, and C/EBP-β protein interactions (please note that this list is not exhaustive, for a more extensive list also visit the GenCards website [41]).

Regulatory factors in C/EBP- transcriptionC/EBP- target genesC/EBP- protein interactions

Sp1 [42]IL-6 [43]CREB1 [44]
CREB/ATF [42]TNF- [21]CRSP3 [45]
SREBP1c [46]IL1- [21]DDIT3/CHOP [47]
RARa [48]IL-8 [49]EP300 [50]
Myb [51]IL-12 [21]HMG-I/HMG-Y [52]
Fra-2 [53]G-CSF or CSF3 [21]HSF-1 [54]
EGR2 or KROX20 [55]Receptors for G-CSF, GM-CSF, M-CSF [21]SWI/SNF complex [56]
STAT-3 [57]MIP1- [43]Sp1 [52]
NFkB [58]Osteopontin [43]TRIM28/KAP1 [59]
C/EBP- [40]CD14 [43]EGR-1/zif268/NGFI-A [60]
MIP1- [15]Smad-3 and Smad-4 [61]
CRP [21]ATF2 [62]
Hemopexin [21]ATF4 [63]
Haptoglobin [15]C/EBP-, , , , [9]
AGP-a1 [21]FKHR [64]
NFkB, P50 subunit [58]
NR3C1 [65]
C-FOS [66]
PPAR- [67, 68]
C/EBP-, , , , [9]
cAMP [69]
Albumin [70]
MDR1 [71]