Potential Peripartum Markers of Infectious-Inflammatory Complications in Spontaneous Preterm Birth

Table 2

LC-SRM assay results.

Acc. #	Protein name (peptide)^a	Peptides^b	Concordance^c			Median ratio to GIS	Median ratio to GIS
				Positive	Negative	Positive	Negative
P0CG48	Polyubiquitin-C	3	49	26	23	1.40	1.04	0.083
P09228	Cystatin-SA	1	—	27	23	0.53	1.09	0.321
P31025	Lipocalin-1	2	46	26	20	0.99	1.61	0.047
P03973	Antileukoproteinase	1	—	27	23	0.49	0.28	0.087
P59666	Neutrophil defensin 3	2	3	—	—	—	—	—
	(IPACIAGER)	—	—	27	23	0.15	0.07	—
	(YGTCIYQGR)	—	—	27	23	0.45	0.15	—
P09466	Glycodelin	2	42	23	19	1.64	0.49	0.013
P00915	Carbonic anhydrase 1	2	50	27	23	0.58	0.78	0.756
P07358	Complement component C8 beta chain	2	36	19	17	1.07	0.95	0.568
P02452	Collagen alpha-1(I) chain	3	0	—	—	—	—	—
	(ICVCDNGK)	—	—	27	23	0.43	0.36	—
	(VLCDDVICDETK)	—	—	27	23	0.79	0.64	—
	(SLSQQIENIR)	—	—	27	23	0.97	1.25	—
P60174	Triosephosphate isomerase	3	49	27	22	1.22	0.78	0.169
P60709	Actin, cytoplasmic 1	2	37	19	18	0.70	0.42	0.076
P43490	Nicotinamide phosphoribosyltransferase	2	39	24	20	0.55	0.19	0.018
Q9HC84	Mucin-5B	2	35	22	15	0.94	0.91	0.805
Q9BRK3	Matrix-remodeling-associated protein 8	1	—	27	23	1.07	1.06	0.832
P14384	Carboxypeptidase M	1	—	27	23	0.94	1.29	0.613

In proteins showing low concordance between corresponding peptides, data for individual peptides are presented.
^bNumber of peptides used for LC-SRM quantification of particular protein.
^cNumber of samples in which concordance between corresponding peptides was below RSD of 20%.
^dNumber of samples that fulfilled all requirements and were subjected to statistical analysis.
^e value as calculated by Mann-Whitney test.