High Body Mass Index Is an Indicator of Maternal Hypothyroidism, Hypothyroxinemia, and Thyroid-Peroxidase Antibody Positivity during Early Pregnancy

Table 2

Prevalence of thyroid dysfunctions^b,c.

BMI (Kg/m^2)	Total	Overt; hypothyroidism; (%)	Subclinical hypothyroidism; (%)	Isolated; hypothyroxinemia; (%)	TPOAb positive; (%)	TgAb positive; (%)
Total	6303	63 (1.0)	203 (3.2)	149 (2.4)	578 (9.2)	790 (12.5)
<18.5	870	2 (0.2)	29 (3.3)	11 (1.3)	58 (6.7)	94 (10.8)
18.5–24.9	4547	42 (0.9)	141 (3.1)	87 (1.9)	402 (8.8)	564 (12.4)
25.0–29.9	796	16 (2.0)	26 (3.3)	40 (5.0)	97 (12.2)	114 (14.3)
≥30.0	90	3 (3.3)	7 (7.8)	11 (12.2)	21 (23.3)	18 (20.0)
P value		<0.001	0.101	<0.001	<0.001	0.025
value^a		<0.001	0.340	<0.001	<0.001	0.004

value for trend.
was considered as a significant difference.
^cThe diagnostic standards for thyroid abnormalities were according to the pregnant specific reference ranges of the 4th–8th gestational weeks.