Prognostic Value of Homotypic Cell Internalization by Nonprofessional Phagocytic Cancer Cells
Table 3
Univariate and multivariate overall survival analyses according to Cox’s proportional hazards model and HNSCC adjuvant radiochemotherapy central tumor area collectively.
HNSCC central tumor area;
Univariate analysis
Multivariate analysis
Variable
Hazard ratio
95% C.I.
Hazard ratio
95% C.I.
Age, years (younger than 58 years [] versus older than 58 years [])
1.853
1.007–3.41
0.048
1.559
0.901–2.697
0.113
Gender (male [] versus female [])
1.275
0.566–2.871
0.558
—
—
—
T category (T1/T2 [] versus T3/T4 [])
0.748
0.36–1.554
0.436
—
—
—
N category (N0 [] versus N+ [])
1.080
0.333–3.5
0.899
—
—
—
M-category (M0 [] versus M+ [])
8.094
1.59–41.214
0.012
4.660
1.377–15.767
0.013
Stage (UICC I [] versus UICC II and higher [])
0.971
0.309–3.053
0.960
—
—
—
Grade (1 + 2 [] versus 3 + 4 [])
0.987
0.526–1.851
0.967
—
—
—
CIC (0/mm² [] versus >0/mm² [])
2.555
1.334–4.894
0.005
2.139
1.215–3.764
0.008
Apoptotic cells (<9.5/mm² [] versus ≥9.5/mm² [])
1.037
0.329–3.266
0.950
—
—
—
Proliferating cells (<122/mm² [] versus ≥122/mm² [])
